Projects per year
Personal profile
Research interests
Research Expertise:
Drug Discovery | Reaction Invention | Organic Synthesis
My background is in synthetic organic chemistry with an emphasis in methods development and library synthesis. My research group is focused on developing novel reactions for the synthesis of biologically relevant molecular scaffolds. Our central hypothesis is to invent organic reactions to access biologically relevant molecular targets. Thus, I have a number of projects dedicated to the synthesis of small molecule libraries with a diverse array of biological properties and to the discovery of novel reaction pathways for the synthesis of complex molecular scaffolds.
Projects:
Novel Methods for the Synthesis of Small Heterocycles, Synthesis of Pharmacologically Relevant Molecular Scaffolds, Photoredox Catalysis for New Reaction Discovery, Isolation and Characterization of Natural Products from Peruvian Medicinal Plants, Development of Novel Drugs for the Treatment of Diabetes and Cardiovascular Diseases, Novel Alkaloid-like Scaffolds as Highly Potent Analgesics Without side Effects.
Award:
2018 NSF CAREER: The Faculty Early Career Development (CAREER) Program Award
Member of:
American Chemical Society Division of Organic Chemistry (ACS)
Recent Academic Projects:
Developing workshop-like certificate program for returning veterans in chemistry instrumentation.
Education/Academic qualification
Doctor of Philosophy, doctorate, University of Pittsburgh
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Deconstructing Diazepines: Novel Approaches to their Systematic Synthesis
Moura, G. (PI)
National Institutes of Health (NIH)
8/1/23 → 4/30/26
Project: Other project
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Metallooxaziridines for the Synthesis of Nitrogen-Containing Three-Membered Heterocycles
Moura, G. (PI)
5/1/18 → 4/30/25
Project: Other project
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Development of Highly Selective COVID-19 Inhibitors
Moura, G. (PI)
New Jersey Health Foundation, Inc. (NJHF)
1/11/21 → 1/10/23
Project: Other project
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From Heterocycles to Cyclic Hydrocarbons: A Reconstructive Approach to Complex Hydrocarbons
Moura, G. (PI)
American Chemical Society- Petroleum Research Fund (ACS PRF)
1/1/21 → 8/31/24
Project: Other project
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MRI: Acquisition of a 400 MHz Nuclear Magnetic Resonance Spectrometer for the Transformative Advancement of Undergraduate Research
Moura, G. (PI)
1/2/19 → 1/2/20
Project: Other project
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Synthesis of Vinyl Sulfones from Substituted Alkenes via Molybdooxaziridine Catalysis
Doran, E. L., Doran, J. M., Pinarci, A. A., Rossi, M. E., Madiu, R., Howard, A. M., Stroud, J. L., Rivera, D. A., Moskovitz, D. A., Singer, A. N., Finneran, S. J. & Moura-Letts, G., 2025, (Accepted/In press) In: European Journal of Organic Chemistry.Research output: Contribution to journal › Article › peer-review
Open Access -
Synthesis of aminoalcohols from substituted alkenes via tungstenooxaziridine catalysis
Madiu, R., Dellosso, B., Doran, E. L., Doran, J. M., Pinarci, A. A., TenHoeve, T. M., Howard, A. M., Stroud, J. L., Rivera, D. A., Moskovitz, D. A., Finneran, S. J., Singer, A. N., Rossi, M. E. & Moura-Letts, G., Feb 21 2024, In: Organic and Biomolecular Chemistry. 22, 11, p. 2300-2306 7 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Synthesis of N-Tosyl Allylic Amines from Substituted Alkenes via Vanadoxaziridine Catalysis
Madiu, R., Doran, E. L., Doran, J. M., Pinarci, A. A., Dhillon, K., Rivera, D. A., Howard, A. M., Stroud, J. L., Moskovitz, D. A., Finneran, S. J., Singer, A. N., Rossi, M. E. & Moura-Letts, G., Mar 15 2024, In: Journal of Organic Chemistry. 89, 6, p. 4001-4008 8 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Synthesis of Isoxazolidines from Substituted Vinylnitrones and Conjugated Carbonyls via Visible-Light Photocatalysis
Trieu, P., Filkin, W. H., Pinarci, A., Tobias, E. M., Madiu, R., Dellosso, B., Roldan, J., Das, P., Austin, B. E. & Moura-Letts, G., Mar 2023, In: ChemPhotoChem. 7, 3, e202200277.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Visible-Light-Promoted Synthesis of Vinyloxaziridines from Conjugated Carbonyls
Austin, B. E., Palner, R. P., Tobias, E. M., Madiu, R., Doran, E. L., Doran, J. M., Howard, A. M., Stroud, J. L., Rossi, M. E., Moskovitz, D. A., Rivera, D. A., Mullen, M. D., Zinsky, A. H., Rosario, R. A. & Moura-Letts, G., May 31 2023, In: Synlett. 35, 3, p. 325-329 5 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations