Projects per year
Personal profile
Research interests
My research interests are in two major areas: designing/characterizing peptides with specific functions and antimicrobial surfaces.
The majority of the research focuses on the development and characterization of antimicrobial peptides. These are short, cationic sequences that are highly effective, broad spectrum antimicrobials with low toxicity profiles. I study the chemical and amino-acid composition of these peptides and the role different amino acids play in the functional properties of these peptides. My lab also has a project focused on the design of peptides to interact with optically active porphyrins toward the development of novel materials for application in photovoltaic devices.
I also am interested in antimicrobial thin film coatings. In collaboration with the Departments of Physics & Astronomy and Electrical & Computer Engineering, my team has developed a series of coatings (patent pending) with a variety of antimicrobial and physical properties. The group focuses on the efficacy and mechanism of the antimicrobial coatings.
Education/Academic qualification
Doctor of Philosophy, doctorate
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Collaborations and top research areas from the last five years
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Development of novel, daptomycin-inspired antimicrobial peptides using non-canonical amino acids
Caputo, G. (PI)
National Institutes of Health (NIH)
12/20/24 → 11/30/27
Project: Other project
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Antimicrobial and solubility investigation of coated materials
Caputo, G. (PI)
6/1/22 → 12/31/22
Project: Other project
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Metallic nanocluster structure fluctuations as an early detector of cancer biomarkers
Caputo, G. (PI)
Virginia Commonwealth University
7/1/20 → 6/30/23
Project: Other project
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Lipid bilayer permeabilities and antibiotic effects of tetramethylguanidinium and choline fatty acid ionic liquids
Dutta, A., Burrell, B., Prajapati, E., Cottle, S., Maurer, H. Y., Urban, M. J., Pennock, S. R., Muhamed, A. M., Harris, J., Flores, Y., Staman, L., Carone, B. R., Caputo, G. A. & Vaden, T. D., Jan 2025, In: Biochimica et Biophysica Acta - Biomembranes. 1867, 1, 184393.Research output: Contribution to journal › Article › peer-review
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Cluster-Enhanced Nanopore Sensing of Ovarian Cancer Marker Peptides in Urine
Rockett, T. W., Almahyawi, M., Ghimire, M. L., Jonnalagadda, A., Tagliaferro, V., Seashols-Williams, S. J., Bertino, M. F., Caputo, G. A. & Reiner, J. E., Feb 23 2024, In: ACS Sensors. 9, 2, p. 860-869 10 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Hierarchical Surface Restructuring of Ultra-Thin Electrodes and Microelectrode Arrays for Neural Interfacing with Peripheral and Central Nervous Systems
Blagojevic, A., Seche, W., Choi, H., Davis, S. L., Elyahoodayan, S., Caputo, G. A., Lowe, T. C., Tavousi, P., Shahbazmohamadi, S. & Amini, S., Aug 14 2024, In: Advanced Materials Interfaces. 11, 23, 2400017.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Sustainability inspired fabrication of next generation neurostimulation and cardiac rhythm management electrodes via reactive hierarchical surface restructuring
Amini, S., Choi, H., Seche, W., Blagojevic, A., May, N., Lefler, B. M., Davis, S. L., Elyahoodayan, S., Tavousi, P., May, S. J., Caputo, G. A., Lowe, T. C., Hettinger, J. & Shahbazmohamadi, S., Dec 2024, In: Microsystems and Nanoengineering. 10, 1, 125.Research output: Contribution to journal › Article › peer-review
Open Access -
Biomimetic antimicrobial polymers—Design, characterization, antimicrobial, and novel applications
Takahashi, H., Sovadinova, I., Yasuhara, K., Vemparala, S., Caputo, G. A. & Kuroda, K., May 1 2023, In: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 15, 3, e1866.Research output: Contribution to journal › Review article › peer-review
Open Access11 Scopus citations