Research Output per year
Research Output per year
Personal profile
Research interests
My research interests are in two major areas: designing/characterizing peptides with specific functions and antimicrobial surfaces.
The majority of the research focuses on the development and characterization of antimicrobial peptides. These are short, cationic sequences that are highly effective, broad spectrum antimicrobials with low toxicity profiles. I study the chemical and amino-acid composition of these peptides and the role different amino acids play in the functional properties of these peptides. My lab also has a project focused on the design of peptides to interact with optically active porphyrins toward the development of novel materials for application in photovoltaic devices.
I also am interested in antimicrobial thin film coatings. In collaboration with the Departments of Physics & Astronomy and Electrical & Computer Engineering, my team has developed a series of coatings (patent pending) with a variety of antimicrobial and physical properties. The group focuses on the efficacy and mechanism of the antimicrobial coatings.
Education/Academic qualification
Doctor of Philosophy, doctorate
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Research Output
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Synergistic interactions of ionic liquids and antimicrobials improve drug efficacy
Yang, D. D., Paterna, N. J., Senetra, A. S., Casey, K. R., Trieu, P. D., Caputo, G. A., Vaden, T. D. & Carone, B. R., Jan 22 2021, In: iScience. 24, 1, 101853.Research output: Contribution to journal › Article › peer-review
Open Access -
Cationic Molecular Umbrellas as Antibacterial Agents with Remarkable Cell-Type Selectivity
Chen, A., Karanastasis, A., Casey, K. R., Necelis, M., Carone, B. R., Caputo, G. A. & Palermo, E. F., Jan 1 2020, (Accepted/In press) In: ACS Applied Materials and Interfaces.Research output: Contribution to journal › Review article › peer-review
4 Scopus citations -
Effect of Non-natural Hydrophobic Amino Acids on the Efficacy and Properties of the Antimicrobial Peptide C18G
Hitchner, M. A., Necelis, M. R., Shirley, D. & Caputo, G. A., 2020, (Accepted/In press) In: Probiotics and Antimicrobial Proteins.Research output: Contribution to journal › Article › peer-review
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Investigation of the structure-activity relationship in ponericin L1 from Neoponera goeldii
Senetra, A. S., Necelis, M. R. & Caputo, G. A., May 1 2020, In: Peptide Science. 112, 3, e24162.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Activity and characterization of a pH-sensitive antimicrobial peptide
Hitchner, M. A., Santiago-Ortiz, L. E., Necelis, M. R., Shirley, D. J., Palmer, T. J., Tarnawsky, K. E., Vaden, T. D. & Caputo, G. A., Oct 1 2019, In: Biochimica et Biophysica Acta - Biomembranes. 1861, 10, 182984.Research output: Contribution to journal › Article › peer-review
7 Scopus citations