Gregory Caputo

Department Head, Associate Professor

  • 1612 Citations
  • 21 h-Index

Research output per year

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Personal profile

Research interests

My research interests are in two major areas: designing/characterizing peptides with specific functions and antimicrobial surfaces.

The majority of the research focuses on the development and characterization of antimicrobial peptides. These are short, cationic sequences that are highly effective, broad spectrum antimicrobials with low toxicity profiles. I study the chemical and amino-acid composition of these peptides and the role different amino acids play in the functional properties of these peptides. My lab also has a project focused on the design of peptides to interact with optically active porphyrins toward the development of novel materials for application in photovoltaic devices.

I also am interested in antimicrobial thin film coatings. In collaboration with the Departments of Physics & Astronomy and Electrical & Computer Engineering, my team has developed a series of coatings (patent pending) with a variety of antimicrobial and physical properties. The group focuses on the efficacy and mechanism of the antimicrobial coatings.

Education/Academic qualification

Doctor of Philosophy, doctorate

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Research Output

  • 1612 Citations
  • 21 h-Index
  • 40 Article
  • 4 Review article
  • 3 Chapter
  • 1 innovation

Cationic Molecular Umbrellas as Antibacterial Agents with Remarkable Cell-Type Selectivity

Chen, A., Karanastasis, A., Casey, K. R., Necelis, M., Carone, B. R., Caputo, G. A. & Palermo, E. F., Jan 1 2020, (Accepted/In press) In : ACS Applied Materials and Interfaces.

Research output: Contribution to journalReview article

  • 1 Scopus citations

    Effect of Non-natural Hydrophobic Amino Acids on the Efficacy and Properties of the Antimicrobial Peptide C18G

    Hitchner, M. A., Necelis, M. R., Shirley, D. & Caputo, G. A., 2020, (Accepted/In press) In : Probiotics and Antimicrobial Proteins.

    Research output: Contribution to journalArticle

  • Investigation of the structure-activity relationship in ponericin L1 from Neoponera goeldii

    Senetra, A. S., Necelis, M. R. & Caputo, G. A., May 1 2020, In : Peptide Science. 112, 3, e24162.

    Research output: Contribution to journalArticle

  • Activity and characterization of a pH-sensitive antimicrobial peptide

    Hitchner, M. A., Santiago-Ortiz, L. E., Necelis, M. R., Shirley, D. J., Palmer, T. J., Tarnawsky, K. E., Vaden, T. D. & Caputo, G. A., Oct 1 2019, In : Biochimica et Biophysica Acta - Biomembranes. 1861, 10, 182984.

    Research output: Contribution to journalArticle

  • 3 Scopus citations

    Analyzing Transmembrane Protein and Hydrophobic Helix Topography by Dual Fluorescence Quenching

    Caputo, G. A. & London, E., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 351-368 18 p. (Methods in Molecular Biology; vol. 2003).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  • 2 Scopus citations