Cristina Iftode

Former affiliation
  • 515 Citations
  • 7 h-Index
19972016
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Personal profile

Research interests

Research Expertise: 
Stem cell differentiation | Replication and transcription of DNA viruses

My research interests are: 1) human stem cells and biomaterials in regenerative medicine, and 2) isolation and characterization of secondary plant metabolites.

1) I study the application of the adipose derived-mesenchymal stem cell (AD-MSC) differentiation to the regeneration of the intervertebral disc tissue. In collaboration with the Departments of Chemical and Mechanical Engineering, my group is using a tissue engineering approach where cell-seeded injectable scaffolds and inducers of differentiation are delivered to the injury site. Characterization of differentiation toward the desired phenotype is assessed by the presence of tissue specific markers. 

In collaboration with the Department of Physics & Astronomy, I examine the medical applicability of protein-based biomaterials in combination with AD-MSCs.

2) I also am interested in culturing methods from meristematic plant cells for the production of secondary plant metabolites (SPMs). Together with a colleague from my department, we are expanding the application of this technique to extracting SPMs from plant species with uses in medicine and cosmetology.

Honors and Awards: 
Rowan University’s Collaborative Innovation in Tissue Engineering Award, 2016

Member of: 
American Society for Cell Biology Chemical Society (www.ascb.org)
American Society for Microbiology (www.asm.org)
American Society for Virology (www.asv.org)

Education/Academic qualification

Bachelor of Science, Bachelor

Master of Science, Master

Doctor of Philosophy, doctorate

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  • 1 Similar Profiles
Tissue engineering Chemical Compounds
Chondroitin Sulfates Chemical Compounds
Tissue Engineering Medicine & Life Sciences
Hydrogels Chemical Compounds
Alginate Engineering & Materials Science
Simian virus 40 Medicine & Life Sciences
Biomimetics Chemical Compounds
DNA Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1997 2016

  • 515 Citations
  • 7 h-Index
  • 8 Article
  • 3 Conference contribution
  • 1 Review article
2 Citations (Scopus)

Synthesis of thermogelling poly(N-isopropylacrylamide)-graft-chondroitin sulfate composites with alginate microparticles for tissue engineering

Christiani, T. R., Toomer, K., Sheehan, J., Nitzl, A., Branda, A., England, E., Graney, P., Iftode, C. & Vernengo, A. J., Oct 26 2016, In : Journal of Visualized Experiments. 2016, 116, e53704.

Research output: Contribution to journalArticle

Chondroitin Sulfates
Alginate
Tissue Engineering
Tissue engineering
Grafts
12 Citations (Scopus)

Thermogelling bioadhesive scaffolds for intervertebral disk tissue engineering: Preliminary in vitro comparison of aldehyde-based versus alginate microparticle-mediated adhesion

Wiltsey, C., Christiani, T., Williams, J., Scaramazza, J., Van Sciver, C. V., Toomer, K., Sheehan, J., Branda, A., Nitzl, A., England, E., Kadlowec, J., Iftode, C. & Vernengo, A., Jan 1 2015, In : Acta Biomaterialia. 16, 1, p. 71-80 10 p.

Research output: Contribution to journalArticle

Chondroitin Sulfates
Intervertebral Disc
Alginate
Tissue Engineering
Scaffolds (biology)
26 Citations (Scopus)

Characterization of injectable hydrogels based on poly(N- isopropylacrylamide)-g-chondroitin sulfate with adhesive properties for nucleus pulposus tissue engineering

Wiltsey, C., Kubinski, P., Christiani, T., Toomer, K., Sheehan, J., Branda, A., Kadlowec, J., Iftode, C. & Vernengo, A., Apr 1 2013, In : Journal of Materials Science: Materials in Medicine. 24, 4, p. 837-847 11 p.

Research output: Contribution to journalArticle

Hydrogels
Chondroitin Sulfates
Tissue Engineering
Tissue engineering
Grafts
1 Citation (Scopus)

Biomimetic hydrogels for tissue engineering of the intervertebral disc

Wiltsey, C. T., Christiani, T. R., Williams, J., Coulter, J. L., Demiduke, D. N., Toomer, K. A., English, S. M., Hess, B. A., Branda, A. M., Sheehan, J., Kadlowec, J., Tulenko, T., Iftode, C. & Vernengo, A., Jun 29 2012, 2012 38th Annual Northeast Bioengineering Conference, NEBEC 2012. p. 394-395 2 p. 6207130. (2012 38th Annual Northeast Bioengineering Conference, NEBEC 2012).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hydrogels
Chondroitin Sulfates
Biomimetics
Tissue engineering
Polymers

Tissue engineering of the intervertebral disc

Wiltsey, C., Christiani, T., Williams, J., Coulter, J., Demiduke, D., Toomer, K., English, S., Hess, B., Branda, A., Sheehan, J., Kadlowec, J., Tulenko, T., Iftode, C. & Vernengo, A., Dec 1 2012, ASME 2012 Summer Bioengineering Conference, SBC 2012. p. 829-830 2 p. (ASME 2012 Summer Bioengineering Conference, SBC 2012).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Tissue engineering