Projects per year
Personal profile
Research interests
Research Expertise:
Virology | Cell biology | Molecular and structural biology
My lab focuses on the interactions between herpes simplex virus (HSV) and its human host. To identify new therapeutic targets, we use molecular and cellular approaches to understand host-virus interactions and responses to infection. We study the mechanism by which HSV binds to cellular receptors in order to design inhibitors of virus entry. We also characterize cellular responses to identify factors involved in susceptibility to HSV infection. Finally, we also are interested in the effects of human saliva on the susceptibility to infection by HSV. This combination of approaches aims at identifying new biomarkers for HSV susceptibility and discovering novel targets for innovative antiviral targets for innovative therapies. We recently interested in identifying and developing new compounds that can inhibit HSV infection and spread.
Honors and Awards:
Joseph and Josephine Rabinowitz Award for Scientific Excellence at the PENN Dental School (2007)
Stephen L Sacks Investigator Award from the American Herpes Foundation (2005)
Frances R Lax Award for Faculty Development at Rowan University (2015)
Member of:
American Society for Microbiology (http://www.asm.org/)
American Association for the Advancement of Science (http://www.aaas.org/)
American Society for Virology (http://www.asv.org)
Education/Academic qualification
Doctor of Philosophy, doctorate, University of Lausanne
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Network
Projects
- 3 Finished
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Developing Broad-Range Antiviral Peptides Against Herpesviruses and Coronaviruses
New Jersey Health Foundation, Inc. (NJHF)
2/15/22 → 2/14/23
Project: Other project
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Adhesion molecules involved in cancer innate immunity
New Jersey Health Foundation, Inc. (NJHF)
2/17/20 → 3/31/21
Project: Other project
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Development of small inhibitors of herpes simplex virus infection.
New Jersey Health Foundation, Inc.
3/1/18 → 2/28/20
Project: Other project
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A high-throughput neutralizing assay for antibodies and sera evaluation against Epstein-Barr virus
Zhong, L., Krummenacher, C., Zhang, W., Hong, J., Feng, Q., Zhao, Q., Chen, Y., Zeng, M. S., Zeng, Y. X., Xu, M. & Zhang, X., Dec 2022, In: Virology Journal. 19, 1, 196.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Urgency and necessity of Epstein-Barr virus prophylactic vaccines
Zhong, L., Krummenacher, C., Zhang, W., Hong, J., Feng, Q., Chen, Y., Zhao, Q., Zeng, M. S., Zeng, Y. X., Xu, M. & Zhang, X., Dec 2022, In: npj Vaccines. 7, 1, 159.Research output: Contribution to journal › Review article › peer-review
Open Access -
Dose-dependent outcome of ebv infection of humanized mice based on green raji unit (Gru) doses
Chen, H., Zhong, L., Zhang, W., Zhang, S., Hong, J., Zhou, X., Zhang, X., Feng, Q., Chen, Y., Zeng, Y. X., Xu, M., Krummenacher, C. & Zhang, X., Nov 2021, In: Viruses. 13, 11, 2184.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
A novel vaccine candidate based on chimeric virus-like particle displaying multiple conserved epitope peptides induced neutralizing antibodies against EBV infection
Zhang, X., Zhao, B., Ding, M., Song, S., Kang, Y., Yu, Y., Xu, M., Xiang, T., Gao, L., Feng, Q., Zhao, Q., Zeng, M. S., Krummenacher, C. & Zeng, Y. X., 2020, In: Theranostics. 10, 13, p. 5704-5718 15 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Herpes simplex virus 1 spread in oligodendrocytic cells is highly dependent on MAl proteolipid
López-Guerrero, J. A., de la Nuez, C., Praena, B., Sánchez-León, E., Krummenacher, C. & Bello-Morales, R., Feb 1 2020, In: Journal of virology. 94, 4, e01739-19.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations