Benjamin Carone

  • Source: Scopus
  • Calculated based on no. of publications stored in Pure and citations from Scopus
20072021

Research activity per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Research interests

Research Expertise: 
Epigenetics | Genomics | Histone modifications

My research interests are in the field of Epigenetics, which I approach by working to identify the epigenetic marks and molecular mechanisms responsible for causing and maintaining the inheritance of acquired states.

Investigating the capacity of conserved protein catalytic domains to establish and maintain epigenetic modifications in S. cerevisiae with the ultimate goal establishing the causal role of histone packaging in regulating gene expression. 

Specifically, my laboratory has created a suite of fusion proteins using CRISPR technology to target H3K9me to eGFP tagged endogenous S. cerevisiae genes which we interrogate expression levels using qRT-PCR as flow cytometry.

Testing the hypothesis that mammalian spermatic chromatin is highly organized and that this patterning can function to drive Transgenerational Epigenetic Inheritance.  Determining the genome-wide organization of chromatin in germ cells using genomic and bioinformatics approaches.  We are currently working with previously/externally generated datasets but will also be investigating spermatic chromatin in the context of Ctcf mutant mice at Rowan University as this project matures.

Member of:
American Society for Biochemistry and Molecular Biology (www.asbmb.org)
Genetics Society of America (www.genetics-gsa.org)
Sigma Xi (www.sigmaxi.org)

Education/Academic qualification

Doctor of Philosophy, doctorate, University of Connecticut

Fingerprint

Dive into the research topics where Benjamin Carone is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
  • 2 Similar Profiles

Network

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or