Personal profile
Education/Academic qualification
Doctor of Philosophy, doctorate
Bachelor of Science, Bachelor
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Dive into the research topics where Amanda Fakira is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Targeting PEN-GPR83 as a as a strategy to reduce opioid abuse liability.
Fakira, A. (PI)
National Institutes of Health (NIH)
9/30/24 → 7/31/29
Project: Other project
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The potential of GPR83 antagonist Cpd 25 to alleviate the rewarding and dependence effects of morphine.
Fakira, A. (PI)
Alexandrine and Alexander L. Sinsheimer Foundation
11/9/23 → 6/30/25
Project: Other project
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Mechanisms Underlying Adolescent Stress-Induced Anxiety
Fakira, A. (PI)
New Jersey Health Foundation, Inc. (NJHF)
2/15/23 → 2/14/25
Project: Other project
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Identification of small molecule ligands for GPR83 that modulate morphine antinociception and reward
Gomes, I., Mack, S. M., Sanchez, R., Yadav, A., Duarte, M. L., Devi, L. A. & Fakira, A. K., Jan 2026, In: Molecular Pharmacology. 108, 1, 100092.Research output: Contribution to journal › Article › peer-review
Open Access -
Major-depressive-disorder-associated dysregulation of ZBTB7A in orbitofrontal cortex promotes astrocyte-mediated stress susceptibility
Fulton, S. L., Bendl, J., Di Salvo, G., Fullard, J. F., Al-Kachak, A., Lepack, A. E., Stewart, A. F., Singh, S., Poller, W. F., Bastle, R. M., Hauberg, M. E., Fakira, A. K., Patel, V., Chen, M., Durand-de Cuttoli, R., Gameiro-Ros, I., Cathomas, F., Ramakrishnan, A., Gleason, K. & Shen, L. & 9 others, , Aug 20 2025, In: Neuron. 113, 16, p. 2656-2672.e13Research output: Contribution to journal › Article › peer-review
Open Access6 Link opens in a new tab Scopus citations -
ProSAAS neuropeptides and receptors GPR171 and GPR83: Potential therapeutic applications for pain, anxiety, and body weight regulation
Fricker, L. D., Fakira, A. K., Bobeck, E. N., Raddatz, M., Kim, K., DeSchepper, K. D. & Morgan, D. J., Jun 2025, In: Journal of Pharmacology and Experimental Therapeutics. 392, 6, 103599.Research output: Contribution to journal › Review article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Multiomics Analyses Identify Proline Endopeptidase-Like Protein As a Key Regulator of Protein Trafficking, a Pathway Underlying Alzheimer's Disease Pathogenesis
Duarte, M. L., Wang, M., Gomes, I., Liu, C., Sharma, A., Fakira, A. K., Gupta, A., MacK, S. M., Zhang, B. & Devi, L. A., Jul 1 2023, In: Molecular Pharmacology. 104, 1, p. 1-16 16 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Link opens in a new tab Scopus citations -
GPR83 Engages Endogenous Peptides from Two Distinct Precursors to Elicit Differential SignalingS
Mack, S. M., Gomes, I., Fakira, A. K., Duarte, M. L., Fricker, A. G. L. & Devi, L. A., Jul 1 2022, In: Molecular Pharmacology. 102, 1, p. 29-38 10 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Link opens in a new tab Scopus citations