Alison Krufka

  • 1406 Citations
  • 5 h-Index
1991 …2022
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Personal profile

Research interests

Research Expertise: 
Discipline Based Education Research | Evolution and development of the lateral line system | Urea cycle function and evolution

My research focuses on effective ways to integrate scientific skills, authentic inquiry, and an understanding science into undergraduate curricula. I am working on three projects that incorporate scientific skills and inquiry into the classroom: 1) integration of biology and engineering through development of inquiry based cell culture technology and biomaterials lab modules, 2) study of the effective implementation of the CREATE approach to teaching the process of scientific inquiry through directed analysis of primary literature, and 3) the development/assessment of a scientific skills based transfer student course.

I am investigating the evolution and embryonic development of lateral line system using threespine stickleback. We seek to understand how adult variation in the number and size of neuromast sensory organs are generated during embryonic development. I also am interested in the evolutionary conservation of urea cycle genes. We hypothesize the urea cycle genes function in  embryos prior to the formation of ammonia excretion pathways and protect the developing brain from the breakdown of yolk proteins. The conservation of urea cycle genes from fish to mammals allows us to study urea cycle disorders and the toxicity of hyperammonemia on brain development using the zebrafish model.

Member of:
American Association for the Advancement of Science
American Society for Cell Biology
Society for Developmental Biology

Recent Academic Projects:
I serve as the Program Director of the Cumberland County College Bridge to Rowan University NIH-sponsored Bridges to the Baccalaureate Program.

Education/Academic qualification

Doctor of Philosophy, doctorate

Bachelor of Science, Bachelor

Fingerprint Dive into the research topics where Alison Krufka is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Heparitin Sulfate Medicine & Life Sciences
Fibroblast Growth Factor 2 Medicine & Life Sciences
Zebrafish Medicine & Life Sciences
Amino-Acid N-Acetyltransferase Medicine & Life Sciences
Clustered Regularly Interspaced Short Palindromic Repeats Medicine & Life Sciences
Literature Medicine & Life Sciences
Catenins Medicine & Life Sciences
Connexin 43 Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2013 2022

Research Output 1991 2019

  • 1406 Citations
  • 5 h-Index
  • 7 Article
  • 1 Review article

Integrating CRISPR-Cas9 technology into undergraduate courses: Perspectives from a National Science Foundation (NSF) workshop for undergraduate faculty, June 2018

Wolyniak, M. J., Austin, S., Bloodworth, L. F., Carter, D., Harrison, S. H., Hoage, T., Hollis-Brown, L., Jefferson, F., Krufka, A., Safadi-Chamberlin, F., Santisteban, M. S., Soneral, P., Van Winkle, B. & Challa, A. K., Jan 1 2019, In : Journal of Microbiology and Biology Education. 20, 1

Research output: Contribution to journalReview article

Open Access
Clustered Regularly Interspaced Short Palindromic Repeats
college students
Workflow
workflow
teachers
Literature
Microbiology
Students
Atmosphere
Teaching
4 Citations (Scopus)

Expression pattern and biochemical properties of zebrafish N-acetylglutamate synthase

Caldovic, L., Haskins, N., Mumo, A., Majumdar, H., Pinter, M., Tuchman, M. & Krufka, A., Jan 22 2014, In : PloS one. 9, 1, e85597.

Research output: Contribution to journalArticle

Amino-Acid N-Acetyltransferase
Zebrafish
Danio rerio
urea
arginine
25 Citations (Scopus)

Developmental regulation and expression of the zebrafish connexin43 gene

Chatterjee, B., Chin, A. J., Valdimarsson, G., Finis, C., Sonntag, J. M., Choi, B. Y., Tao, L., Balasubramanian, K., Bell, C., Krufka, A., Kozlowski, D. J., Johnson, R. G. & Lo, C. W., Jul 1 2005, In : Developmental Dynamics. 233, 3, p. 890-906 17 p.

Research output: Contribution to journalArticle

Connexin 43
Zebrafish
Genes
Mammalian Embryo
Developmental Genes
17 Citations (Scopus)

Evidence that dorsal-ventral differences in gap junctional communication in the early Xenopus embryo are generated by β-catenin independent of cell adhesion effects

Krufka, A., Johnson, R. G., Wylie, C. C. & Heasman, J., Aug 1 1998, In : Developmental Biology. 200, 1, p. 92-102 11 p.

Research output: Contribution to journalArticle

Catenins
Xenopus
Cell Adhesion
Embryonic Structures
Communication